Gangrene - Medical Glossary

Understanding Gangrene and How It Develops?

Gangrene occurs when blood supply to an area is cut off, leading to tissue death. It can result from conditions like diabetes, peripheral artery disease, frostbite, or severe injury. Infections, especially by bacteria such as Clostridium, can produce gas gangrene, a rapidly spreading and life-threatening form.

Symptoms and Types of Gangrene?

Symptoms include severe pain, swelling, discoloration of the affected area (black, green, or purple), foul-smelling discharge, and skin blisters. Types include dry gangrene (slow tissue death), wet gangrene (caused by infection), and gas gangrene (producing gas under the skin and spreading quickly).

Causes and Risk Factors for Gangrene?

Risk factors include diabetes, smoking, vascular disease, severe injuries, and compromised immune function. Poor circulation, frostbite, and infections increase susceptibility. Prompt wound care, good hygiene, and managing chronic health conditions reduce the risk of gangrene.

Treatment Options for Gangrene?

Treatment depends on the type and severity. It may include surgical removal of dead tissue, antibiotics to fight infection, and restoring blood flow to the affected area. In severe cases, amputation might be necessary. Early treatment significantly improves outcomes.

When to Seek Medical Help for Gangrene?

Seek immediate medical care if you notice sudden pain, swelling, discoloration, or foul odor from a wound. Early signs of infection or numbness in a limb require urgent evaluation. Timely treatment can prevent severe complications and save tissue and life.